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Not medical advice. A living research archive of historical and continually changing sources, for research and personal reference only. Summaries are paraphrases — verify against the originals. Full disclaimer
Not medical advice. A living research archive of historical and continually changing sources, for research and personal reference only. Summaries are paraphrases — verify against the originals. Full disclaimer
For research coding — not for diagnosis
| ICD-10-CM | ICD-11 | How it fits |
|---|---|---|
| F52.0 Hypoactive sexual desire disorder | HA00 Hypoactive sexual desire dysfunction | Core match for loss-of-libido criterion. Note: F52.0's tabular header excludes substance-induced cases; use alongside T-codes for post-drug framing. |
| F52.21 Male erectile disorder | HA01.1 Male erectile dysfunction | Core match for ED criterion (males). Use HA01.12 (acquired, generalised) in ICD-11 when post-drug onset is documented. |
| N52.2 Drug-induced erectile dysfunction | HA01.1 + NE60 (postcoordinated) Male erectile dysfunction + harmful effect of drug (cluster) | ICD-10-CM N52.2 explicitly captures drug-induced ED; pair with T-code for the agent. Useful for PFS cases where ED dominates. |
| F52.22 Female sexual arousal disorder | HA01.0 Female sexual arousal dysfunction | Female arousal/lubrication complaints (Healy 2022 ancillary: decreased vaginal lubrication). |
| F52.31 Female orgasmic disorder | HA02.0 Anorgasmia | Female orgasmic dysfunction / pleasureless orgasm. |
| F52.32 Male orgasmic disorder | HA02.0 Anorgasmia | Male anorgasmia / markedly diminished orgasmic sensation. Tabular includes delayed ejaculation. |
| F52.32 Male orgasmic disorder (delayed ejaculation inclusion term) | HA03.1 Male delayed ejaculation | For reduced ejaculatory force / delayed ejaculation (Healy 2022 ancillary symptom in males). |
| F52.4 Premature ejaculation | HA03.0 Male early ejaculation | Less central to PFS/PSSD; include for completeness of ejaculatory-dysfunction queries. |
| F52.8 Other sexual dysfunction not due to a substance or known physiological condition | HA0Y Other specified sexual dysfunctions | Catch-all for atypical presentations (e.g., flaccid glans during erection, reduced nipple sensitivity). |
| F52.9 Unspecified sexual dysfunction not due to a substance or known physiological condition | HA0Z Sexual dysfunctions, unspecified | Last-resort code; Healy 2024 notes cases scatter under vague labels like this. |
| ICD-10-CM | ICD-11 | How it fits |
|---|---|---|
| R20.0 Anesthesia of skin | MB40.3 Anaesthesia of skin | Best proxy for genital anesthesia/numbness. Symptom code; not a principal diagnosis once a definitive diagnosis is established. |
| R20.1 Hypoesthesia of skin | ME65 (parent) Disturbances of skin sensation of unspecified aetiology | Reduced genital sensitivity (partial loss). |
| R20.2 Paresthesia of skin | ME65.4 Tingling of skin | Tingling / pins-and-needles sensations; inclusion terms cover formication and tingling. |
| R20.8 Other disturbances of skin sensation | ME65.Y Other specified disturbance of skin sensation | Atypical sensory complaints not fitting above (e.g., altered erogenous sensation quality). |
| R20.9 Unspecified disturbances of skin sensation | ME65.Z Disturbances of skin sensation of unspecified aetiology, unspecified | Unspecified sensory complaint; verify ME65.Z in the WHO ICD-11 browser before use. |
| ICD-10-CM | ICD-11 | How it fits |
|---|---|---|
| F32.9 Major depressive disorder, single episode, unspecified | 6A70 Single episode depressive disorder | Depressive presentations; specify severity (F32.0-F32.3) when documented. |
| F33.9 Major depressive disorder, recurrent, unspecified | 6A71 Recurrent depressive disorder | Recurrent course; specify severity (F33.0-F33.2) when documented. |
| F32.A Depression, unspecified | 6A70 / 6A71 (per course) Single episode / recurrent depressive disorder | Added FY2025 for depression below full MDD criteria; commonly used when severity is undocumented. |
| F41.1 Generalized anxiety disorder | 6B00 Generalised anxiety disorder | Anxiety domain; #1 most-billed behavioral-health dx in the US. |
| R45.84 Anhedonia | (no standalone code; capture under 6A70/6A71) n/a — anhedonia is a defining symptom of depressive disorders in ICD-11 | Billable ICD-10-CM symptom code (FY2027 valid). Central to the anhedonia/low-libido PFS/PSSD subtype discussed in the corpus. |
| F48.1 Depersonalization-derealization disorder | 6B66 Depersonalisation-derealisation disorder | Healy 2022 ancillary non-sexual symptom (depersonalization). Verify 6B66 in WHO browser. |
| ICD-10-CM | ICD-11 | How it fits |
|---|---|---|
| R41.84 Other specified cognitive deficit | 6D71 Mild neurocognitive disorder | Best proxy for 'brain fog.' ICD-10-CM: code first the underlying condition if known. ICD-11 6D71 explicitly allows medication/substance-related etiology — highly relevant to post-drug framing. |
| R41.840 Attention and concentration deficit | 6D71 Mild neurocognitive disorder | More specific sub-code when attention/concentration is the documented deficit. |
| G47.00 Insomnia, unspecified | 7A00 Insomnia (chronic insomnia disorder grouping 7A00-7A0Z) | Sleep-disorder domain; use G47.0x subtypes when documented. |
| ICD-10-CM | ICD-11 | How it fits |
|---|---|---|
| R45.851 Suicidal ideations | MB26.A Suicidal ideation | Billable symptom code in both systems. Secondary code; pair with mood-disorder code when applicable. |
| T14.91XA Suicide attempt, initial encounter | MB23.R Suicide attempt (exclusion reference of MB26.A) | For attempt events (distinct from ideation). Verify MB23.R in WHO browser. |
| Z13.31 Encounter for screening for depression | QA45 (encounter for screening; verify) Screening encounter (verify exact QA code in WHO browser) | Screening code commonly used in research extracts to flag at-risk cohorts. Verify Z13.31/QA mapping against official tabulars before use. |
| Z91.5 Personal history of self-harm | QC4B Personal history of self-harm (exclusion reference of MB26.A) | History flag for longitudinal registry datasets. |
| ICD-10-CM | ICD-11 | How it fits |
|---|---|---|
| T43.225A / T43.225D / T43.225S Adverse effect of selective serotonin reuptake inhibitors (initial / subsequent / sequela) | NE60 + causative-agent postcoordination Harmful effects of drugs, medicaments or biological substances, NEC — cluster with the specific SRI | Direct T-code for SSRI adverse effects. The S (sequela) 7th character is the most appropriate for PSSD as a persistent post-discontinuation state. |
| T43.215A / T43.215D / T43.215S Adverse effect of selective serotonin and norepinephrine reuptake inhibitors | NE60 + causative-agent postcoordination Harmful effects of drugs, medicaments or biological substances, NEC | SNRI-triggered cases (Healy 2022: SRIs include SNRIs). |
| T43.205A / T43.205D / T43.205S Adverse effect of unspecified antidepressants | NE60 + causative-agent postcoordination Harmful effects of drugs, medicaments or biological substances, NEC | Fallback when the antidepressant class is undocumented. |
| T50.995A / T50.995D / T50.995S Adverse effect of other drugs, medicaments and biological substances | NE60 + causative-agent postcoordination Harmful effects of drugs, medicaments or biological substances, NEC | Bucket for finasteride, dutasteride, and isotretinoin — none has a dedicated ICD-10-CM T-code (finasteride is not a hormone, so T38 does not apply). S (sequela) 7th character fits PFS/PRSD persistence. |
| T88.7XXA Unspecified adverse effect of drug or medicament, initial encounter | NE60 Harmful effects of drugs, medicaments or biological substances, NEC | Only when the drug cannot be identified; prefer specific T-codes above. |