Effect of Acitretin on Penile Erection in Psoriatic Male Patients
The Egyptian Journal of Hospital Medicine2023
Summary (paraphrased)
Noting case reports that retinoids may impair sexual function, this study prospectively assessed penile erection in 31 men with psoriasis treated with the systemic retinoid acitretin for at least two months. Erectile function was measured with the IIEF-5 questionnaire before treatment and again after two months of therapy. The design directly tests whether a retinoid other than isotretinoin affects erectile function in a clinical population, extending the retinoid-sexual dysfunction question beyond acne treatment.
Why it’s in the corpus
One of the few prospective studies measuring erectile function with a validated instrument under a systemic retinoid — extends PRSD evidence from isotretinoin to the retinoid class as a whole.