Powers · Reddit postCore corpus

How many PFS patients has Dr Powers helped?

u/drwillpowers

r/DrWillPowers2021 (per wiki citation)

Dr Will Powers’ own statements and theorizing

Paraphrased from his public posts and talks. His mechanistic and genetic claims are unpublished hypotheses — read them as “Powers theorizes…”, not as established fact.

Mentions treatments or doses — not guidance

Recorded as research context only. Nothing here is a recommendation, and some self-experiments described in sources may be dangerous. Talk to a clinician before changing anything.

Summary (paraphrased)

A 2021 discussion thread on his subreddit about his clinical experience with PFS patients, including a patient describing a decade of persistent symptoms after a finasteride dose change. Captures the early stage of his PFS work, before the later neurosteroid-excess model, and shows patient-reported outcomes being discussed openly on his subreddit.

Why it’s in the corpus

Historical anchor for Powers' PFS involvement timeline; useful for tracking how his model evolved between 2020–2021 and 2026.

Some fields on this page come from the release’s Markdown edition, which carries text the JSON edition omits.

Video
What's Happening to Androgen Metabolism in PFS? Dr. Will Powers #finasteride #podcast
Dr. Will Powers · SIDEfxHUB · short (<60s)
Clip from the summit interview in which Powers discusses androgen metabolism in PFS patients and how hormonal pathways may be altered after finasteride exposure. The description frames understanding these altered pathways as key to identifying underlying…
TALK-adfZxdlmPAkcirca May 2026 (approximate)PFSCore corpus
Video
What's Happening to Androgen Metabolism in PFS? Dr. Will Powers #finasteride #podcast
Dr. Will Powers · Moral Medicine · 1:35 (95s)
PFS androgen metabolism; genetic redundancy model
YT-adfZxdlmPAk2026-05-08PFSCore corpus
Peer-reviewed paperPSSD Discord pick
Analysis of the finasteride treatment and its withdrawal in the rat hypothalamus and hippocampus at whole-transcriptome level
S Giatti, L Cioffi, S Diviccaro, R Piazza, R C Melcangi · Journal of Endocrinological Investigation
Whole-transcriptome (RNA-seq) analysis of hypothalamus and hippocampus in adult male rats treated with finasteride for 20 days and examined 24 h after last dose and 1 month after withdrawal. Treatment altered 186 genes in hypothalamus and 19 in hippocampus…
DISC-0122024PFSPSSD Discord picks

Summary (paraphrased)

Related records

Video

What's Happening to Androgen Metabolism in PFS? Dr. Will Powers #finasteride #podcast

Dr. Will Powers · SIDEfxHUB · short (<60s)

Clip from the summit interview in which Powers discusses androgen metabolism in PFS patients and how hormonal pathways may be altered after finasteride exposure. The description frames understanding these altered pathways as key to identifying underlying…

TALK-adfZxdlmPAkcirca May 2026 (approximate)PFSCore corpus

Video

What's Happening to Androgen Metabolism in PFS? Dr. Will Powers #finasteride #podcast

Dr. Will Powers · Moral Medicine · 1:35 (95s)

PFS androgen metabolism; genetic redundancy model

YT-adfZxdlmPAk2026-05-08PFSCore corpus

Peer-reviewed paperPSSD Discord pick

Analysis of the finasteride treatment and its withdrawal in the rat hypothalamus and hippocampus at whole-transcriptome level

S Giatti, L Cioffi, S Diviccaro, R Piazza, R C Melcangi · Journal of Endocrinological Investigation

Whole-transcriptome (RNA-seq) analysis of hypothalamus and hippocampus in adult male rats treated with finasteride for 20 days and examined 24 h after last dose and 1 month after withdrawal. Treatment altered 186 genes in hypothalamus and 19 in hippocampus…

DISC-0122024PFSPSSD Discord picks