Why does PFS cause numbness only in the penis? 2 years off fin, sensation at 5–10%
u/various (r/DrWillPowers members)
r/DrWillPowersnot verified (mirror crawled ~168 days before 2026-10-07)
Presents Dr Will Powers’ theory
Patient / community self-report
Summary (paraphrased)
A PFS patient with isolated genital numbness (normal systemic hormones, no cognitive symptoms) asked Powers about mechanisms for anatomically localized sensory loss — peripheral nerve vs. androgen-receptor vs. neurosteroid-driven sensory processing — and what might restore sensation. The thread highlights an under-discussed PFS phenotype (genital anesthesia with normal labs) that any complete corpus should cover.
Why it’s in the corpus
Documents a PFS sensory phenotype directly relevant to PSSD overlap (genital anesthesia is a hallmark PSSD symptom). Useful for the corpus's PFS-vs-PSSD comparison and for neurosteroid/sensory-mechanism hypotheses.
Some fields on this page come from the release’s Markdown edition, which carries text the JSON edition omits.
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