Pathway candidateNCBI-verifiedprotein-coding

BCL7B

BAF chromatin remodeling complex subunit BCL7B

NCBI Gene: 9275 Ensembl GeneCards UniProt: Q9BQE9

Pathway candidate — not linked to PFS or PSSD by any record here

BCL7B is in the library because it belongs to the epigenetic regulation family. No study, report or commentary in the corpus names it, so a variant in BCL7B is not, by itself, evidence of anything related to post-drug syndromes.

Gene summary

A protein-coding gene on chromosome 7 (epigenetic regulation). Encodes a member of the BCL7 family including BCL7A, BCL7B and BCL7C proteins. This member is BCL7B, which contains a region that is highly similar to the N-terminal segment of BCL7A or BCL7C proteins.

Source: NCBI Gene, accessed 2026-10-07.

Protein reference (UniProt)

Protein: B-cell CLL/lymphoma 7 protein family member B
Function: Positive regulator of apoptosis. Plays a role in the Wnt signaling pathway, negatively regulating the expression of Wnt signaling components CTNNB1 and HMGA1. Involved in cell cycle progression, maintenance of the nuclear structure and stem cell differentiation. May play a role in lung tumor development or progression (By similarity).
Tissue specificity: Ubiquitous.

Source: UniProtKB/Swiss-Prot Q9BQE9, release 2026_03, licensed CC BY 4.0. This is the protein’s normal biology, not evidence about post-drug syndromes; associated conditions are inherited disorders of the gene, not PFS, PSSD or PRSD.

Why its pathway is in the library

Epigenetic persistence is the leading hypothesis for why post-drug syndromes endure after the drug is gone; chromatin regulators are therefore priority candidates in any persistence mechanism.

Written for the whole epigenetic regulation family, not for BCL7B specifically.

Mentioned in 0 corpus records

No corpus record names BCL7B directly yet. It is in the library because it sits in a pathway the corpus tracks (Epigenetic regulation).

Also in epigenetic regulation

All 130 genes

Browse by family on the gene families page.

Pathway candidateNCBI-verifiedprotein-coding

BCL7B

BAF chromatin remodeling complex subunit BCL7B

Chromosome 7Epigenetic regulation

NCBI Gene: 9275 Ensembl GeneCards UniProt: Q9BQE9

Pathway candidate — not linked to PFS or PSSD by any record here

Gene summary

Source: NCBI Gene, accessed 2026-10-07.

Protein reference (UniProt)

Protein: B-cell CLL/lymphoma 7 protein family member B
Function: Positive regulator of apoptosis. Plays a role in the Wnt signaling pathway, negatively regulating the expression of Wnt signaling components CTNNB1 and HMGA1. Involved in cell cycle progression, maintenance of the nuclear structure and stem cell differentiation. May play a role in lung tumor development or progression (By similarity).
Tissue specificity: Ubiquitous.

Why its pathway is in the library

Epigenetic persistence is the leading hypothesis for why post-drug syndromes endure after the drug is gone; chromatin regulators are therefore priority candidates in any persistence mechanism.

Written for the whole epigenetic regulation family, not for BCL7B specifically.

Mentioned in 0 corpus records

No corpus record names BCL7B directly yet. It is in the library because it sits in a pathway the corpus tracks (Epigenetic regulation).

Also in epigenetic regulation

All 130 genes

Browse by family on the gene families page.