Pathway candidateNCBI-verifiedprotein-coding

SLC16A10

solute carrier family 16 member 10

NCBI Gene: 117247 Ensembl GeneCards UniProt: Q8TF71

Pathway candidate — not linked to PFS or PSSD by any record here

SLC16A10 is in the library because it belongs to the drug transporters family. No study, report or commentary in the corpus names it, so a variant in SLC16A10 is not, by itself, evidence of anything related to post-drug syndromes.

Gene summary

A protein-coding gene on chromosome 6 (drug and xenobiotic transporters). SLC16A10 is a member of a family of plasma membrane amino acid transporters that mediate the Na(+)-independent transport of aromatic amino acids across the plasma membrane.

Source: NCBI Gene, accessed 2026-10-07.

Protein reference (UniProt)

Protein: Monocarboxylate transporter 10
Function: Sodium- and proton-independent thyroid hormones and aromatic acids transporter. Mediates both uptake and efflux of 3,5,3'-triiodothyronine (T3) and 3,5,3',5'-tetraiodothyronine (T4) with high affinity, suggesting a role in the homeostasis of thyroid hormone levels. Responsible for low affinity bidirectional transport of the aromatic amino acids, such as phenylalanine, tyrosine, tryptophan and L-3,4-dihydroxyphenylalanine (L-dopa). Plays an important role in homeostasis of aromatic amino acids (By similarity).
Subcellular location: Cell membrane; Basolateral cell membrane.
Tissue specificity: Strongly expressed in kidney and skeletal muscle and at lower level in placenta and heart.

Source: UniProtKB/Swiss-Prot Q8TF71, release 2026_03, licensed CC BY 4.0. This is the protein’s normal biology, not evidence about post-drug syndromes; associated conditions are inherited disorders of the gene, not PFS, PSSD or PRSD.

Why its pathway is in the library

Transporters set systemic exposure to finasteride/SSRIs and clear conjugated steroid metabolites — directly relevant to both drug pharmacokinetics and Powers' clearance-centered PFS mechanism.

Written for the whole drug transporters family, not for SLC16A10 specifically.

Mentioned in 0 corpus records

No corpus record names SLC16A10 directly yet. It is in the library because it sits in a pathway the corpus tracks (Drug transporters).

Also in drug and xenobiotic transporters

All 62 genes

Browse by family on the gene families page.

Protein reference (UniProt)

Protein: Monocarboxylate transporter 10
Function: Sodium- and proton-independent thyroid hormones and aromatic acids transporter. Mediates both uptake and efflux of 3,5,3'-triiodothyronine (T3) and 3,5,3',5'-tetraiodothyronine (T4) with high affinity, suggesting a role in the homeostasis of thyroid hormone levels. Responsible for low affinity bidirectional transport of the aromatic amino acids, such as phenylalanine, tyrosine, tryptophan and L-3,4-dihydroxyphenylalanine (L-dopa). Plays an important role in homeostasis of aromatic amino acids (By similarity).
Subcellular location: Cell membrane; Basolateral cell membrane.
Tissue specificity: Strongly expressed in kidney and skeletal muscle and at lower level in placenta and heart.