Pathway candidateNCBI-verifiedprotein-coding

SLCO3A1

solute carrier organic anion transporter family member 3A1

NCBI Gene: 28232 Ensembl GeneCards UniProt: Q9UIG8

Pathway candidate — not linked to PFS or PSSD by any record here

SLCO3A1 is in the library because it belongs to the drug transporters family. No study, report or commentary in the corpus names it, so a variant in SLCO3A1 is not, by itself, evidence of anything related to post-drug syndromes.

Gene summary

A protein-coding gene on chromosome 15 (drug and xenobiotic transporters). Enables prostaglandin transmembrane transporter activity. Involved in carboxylic acid transport and positive regulation of intracellular signal transduction.

Source: NCBI Gene, accessed 2026-10-07.

Protein reference (UniProt)

Protein: Solute carrier organic anion transporter family member 3A1
Function: Putative organic anion antiporter with apparent broad substrate specificity. Recognizes various substrates including thyroid hormone L-thyroxine, prostanoids such as prostaglandin E1 and E2, bile acids such as taurocholate, glycolate and glycochenodeoxycholate and peptide hormones such as L-arginine vasopressin, likely operating in a tissue-specific manner. The transport mechanism, its electrogenicity and potential tissue-specific counterions remain to be elucidated (Probable). Mediates transport of tryptophan, phenyalanine and tyrosine.
Subcellular location: Basolateral cell membrane; Apical cell membrane; Basal cell membrane.
Tissue specificity: Generally the expression of isoform 1 is higher than that of isoform 2.

Source: UniProtKB/Swiss-Prot Q9UIG8, release 2026_03, licensed CC BY 4.0. This is the protein’s normal biology, not evidence about post-drug syndromes; associated conditions are inherited disorders of the gene, not PFS, PSSD or PRSD.

Why its pathway is in the library

Transporters set systemic exposure to finasteride/SSRIs and clear conjugated steroid metabolites — directly relevant to both drug pharmacokinetics and Powers' clearance-centered PFS mechanism.

Written for the whole drug transporters family, not for SLCO3A1 specifically.

Mentioned in 0 corpus records

No corpus record names SLCO3A1 directly yet. It is in the library because it sits in a pathway the corpus tracks (Drug transporters).

Also in drug and xenobiotic transporters

All 62 genes

Browse by family on the gene families page.

Protein reference (UniProt)

Protein: Solute carrier organic anion transporter family member 3A1
Function: Putative organic anion antiporter with apparent broad substrate specificity. Recognizes various substrates including thyroid hormone L-thyroxine, prostanoids such as prostaglandin E1 and E2, bile acids such as taurocholate, glycolate and glycochenodeoxycholate and peptide hormones such as L-arginine vasopressin, likely operating in a tissue-specific manner. The transport mechanism, its electrogenicity and potential tissue-specific counterions remain to be elucidated (Probable). Mediates transport of tryptophan, phenyalanine and tyrosine.
Subcellular location: Basolateral cell membrane; Apical cell membrane; Basal cell membrane.
Tissue specificity: Generally the expression of isoform 1 is higher than that of isoform 2.