Post-SSRI sexual dysfunction & other enduring sexual dysfunctions
David Healy
Epidemiology and Psychiatric Sciences2019
Summary (paraphrased)
Healy traces the history of enduring sexual dysfunction after antidepressants from 1991 regulator reports through the first formal PSSD descriptions in 2006, arguing the syndrome has major clinical, research, and regulatory implications that psychiatry has been slow to absorb. He discusses how trial design and reporting conventions kept sexual effects invisible, why persistent dysfunction challenges the assumption that drug effects end at discontinuation, and what the phenomenon implies for informed consent. The paper frames PSSD alongside other tardive drug-induced syndromes as a neglected area of pharmacoepidemiology.
Why it’s in the corpus
Concise historical/epidemiological framing of PSSD by the field's central researcher, in a Cambridge journal. Useful as the corpus's "why this matters" narrative citation.
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- Peer-reviewed paperVenue unverified
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Post-finasteride syndrome and post-SSRI sexual dysfunction: two sides of the same coin?
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