Claimed resolution: the mechanism is figured out; treatment optimization and damage-reversal remain
u/drwillpowers
r/PSSD~2 months ago
Dr Will Powers’ own statements and theorizing
Mentions treatments or doses — not guidance
Summary (paraphrased)
In the "melty skin" explainer thread, Powers states the PFS mechanism is figured out; the remaining questions are (1) the best treatment — he reports one working for androgenic-signaling loss and some melty-skin cases, with neurosteroid issues mostly manageable already — and (2) how to undo damage from prolonged hormone-disrupted signaling. He illustrates with an analogy: modern drugs can drop an AIDS patient's viral load in weeks, but reversing end-stage damage takes far longer. He closes by urging readers to read his accumulated posts rather than asking repeat questions.
Key points (paraphrased)
- Claimed resolution: the mechanism is figured out; treatment optimization and damage-reversal remain.
- Treatment reported working for androgenic-signaling loss and some melty-skin cases.
- AIDS analogy: breaking the feedback loop is fast; undoing prolonged damage is slow.
- Community-education push: read the accumulated posts.
Why it’s in the corpus
The claimed-resolution statement in its most compact form, separating cure (breaking the loop) from damage-reversal. Pairs with PRH-1494's longer "PFS is done" statement.
Context — the post Powers was replying toVerbatim third-party text, shown for context only — not Powers’ statement. Usernames removed.ShowHide
Powers' comment replies to [username removed], who thanked him, apologized for repeated questions, and said it sometimes feels like "the end of the road," in the "What is 'melty skin' in pssd/pfs" thread (OP [username removed], r/PSSD).
(Parent context recovered from the r.genit.al mirror on 2026-10-09; Powers' comment text itself is from John's user-provided export.)
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