PSSD Network — Scientific Research program
PSSD Network (patient advocacy and research funding organisation)
pssdnetwork.org2026 (page current; research support expanded February 2025)
Summary (paraphrased)
The PSSD Network's main hub describes its patient-led research program: ongoing support for Dr Roberto Cosimo Melcangi's neuroendocrine work at the University of Milan, and, since February 2025, new support for Dr Ashley Monks (University of Toronto) and Dr Antonei Csoka (Howard University), plus a research-participant and matched-control database. Its linked research-fundraiser page details three funded efforts: the DAWN Study with the Florey Institute of Neuroscience and Mental Health in Melbourne (a population-based study of PSSD mechanisms, phase 1 funded), a joint Csoka/Monks study of PSSD as iatrogenic epigenetic damage affecting neural reward circuitry, and the long-running Melcangi collaboration. The site also maintains a curated literature collection and expert statements.
Why it’s in the corpus
The current map of active patient-funded PSSD science — names the labs, the hypotheses (neuroendocrine mechanisms, iatrogenic epigenetic damage), and the participant database any future cohort work would draw on. High-value gray literature for the corpus's research landscape.
Related records
- Peer-reviewed paperPSSD Discord pickSIDEfxHUB pick
Altered methylation pattern of the SRD5A2 gene in the cerebrospinal fluid of post-finasteride patients: a pilot study
Roberto Cosimo Melcangi, Livio Casarini, Marco Marino, Daniele Santi, Samantha Sperduti, Silvia Giatti, Silvia Diviccaro, Maria Grimoldi… · Endocrine Connections
In this pilot case-control study, 16 PFS patients were compared with 36 controls who had never used finasteride: 18 surgical patients giving cerebrospinal fluid (2 of whom also gave blood) and 18 blood-only donors; controls' mean age was 40.8 years vs 34.5 in…
SRD5A1SRD5A2DISC-0252019PFSPSSDPSSD Discord picks