Pathway candidate — not linked to PFS or PSSD by any record here
Gene summary
A protein-coding gene on chromosome 9 (lipid and cholesterol homeostasis). The protein encoded by this gene belongs to the perilipin family, members of which coat intracellular lipid storage droplets. This protein is associated with the lipid globule surface membrane material, and maybe involved in development and maintenance of adipose tissue.
Source: NCBI Gene, accessed 2026-10-07.
Protein reference (UniProt)
- Protein
Perilipin-2
- Function
Structural component of lipid droplets, which is required for the formation and maintenance of lipid storage droplets.
- Subcellular location
Membrane; Lipid droplet.
- Tissue specificity
Milk lipid globules.
Source: UniProtKB/Swiss-Prot Q99541, release 2026_03, licensed CC BY 4.0. This is the protein’s normal biology, not evidence about post-drug syndromes; associated conditions are inherited disorders of the gene, not PFS, PSSD or PRSD.
Why its pathway is in the library
Cholesterol is the obligate precursor of all steroid hormones; lipid handling sets substrate supply for steroidogenesis and neurosteroid synthesis.
Written for the whole lipid homeostasis family, not for PLIN2 specifically.
Mentioned in 0 corpus records
No corpus record names PLIN2 directly yet. It is in the library because it sits in a pathway the corpus tracks (Lipid homeostasis).
Also in lipid and cholesterol homeostasis
All 19 genes- LRP2
LDL receptor related protein 2
chr 2· Lipid homeostasis· 4 records - APOA1
apolipoprotein A1
chr 11· Lipid homeostasis· Pathway candidate - APOB
apolipoprotein B
chr 2· Lipid homeostasis· Pathway candidate - CUBN
cubilin
chr 10· Lipid homeostasis· Pathway candidate - DGAT1
diacylglycerol O-acyltransferase 1
chr 8· Lipid homeostasis· Pathway candidate - DGAT2
diacylglycerol O-acyltransferase 2
chr 11· Lipid homeostasis· Pathway candidate - FABP4
fatty acid binding protein 4
chr 8· Lipid homeostasis· Pathway candidate - FABP5
fatty acid binding protein 5
chr 8· Lipid homeostasis· Pathway candidate
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