Pathway candidateNCBI-verifiedprotein-coding

CAT

catalase

NCBI Gene: 847 Ensembl GeneCards UniProt: P04040

Pathway candidate — not linked to PFS or PSSD by any record here

CAT is in the library because it belongs to the mitochondria & energy family. No study, report or commentary in the corpus names it, so a variant in CAT is not, by itself, evidence of anything related to post-drug syndromes.

Gene summary

A protein-coding gene on chromosome 11 (mitochondrial function and energy). Encodes catalase, a key antioxidant enzyme in the bodies defense against oxidative stress. Catalase is a heme enzyme that is present in the peroxisome of nearly all aerobic cells.

Source: NCBI Gene, accessed 2026-10-07.

Protein reference (UniProt)

Protein: Catalase
Function: Catalyzes the degradation of hydrogen peroxide (H(2)O(2)) generated by peroxisomal oxidases to water and oxygen, thereby protecting cells from the toxic effects of hydrogen peroxide. Promotes growth of cells including T-cells, B-cells, myeloid leukemia cells, melanoma cells, mastocytoma cells and normal and transformed fibroblast cells.
Subcellular location: Peroxisome matrix.
Associated conditions: Acatalasemia (ACATLAS).

Source: UniProtKB/Swiss-Prot P04040, release 2026_03, licensed CC BY 4.0. This is the protein’s normal biology, not evidence about post-drug syndromes; associated conditions are inherited disorders of the gene, not PFS, PSSD or PRSD.

Why its pathway is in the library

Mitochondrial dysfunction and oxidative stress are reported in PFS/PSSD patient work; energy failure plausibly contributes to fatigue, cognitive, and sexual symptoms.

Written for the whole mitochondria & energy family, not for CAT specifically.

Mentioned in 0 corpus records

No corpus record names CAT directly yet. It is in the library because it sits in a pathway the corpus tracks (Mitochondria & energy).

Also in mitochondrial function and energy

All 33 genes

Browse by family on the gene families page.

Pathway candidateNCBI-verifiedprotein-coding

CAT

catalase

Chromosome 11Mitochondria & energy

NCBI Gene: 847 Ensembl GeneCards UniProt: P04040

Pathway candidate — not linked to PFS or PSSD by any record here

Gene summary

Source: NCBI Gene, accessed 2026-10-07.

Protein reference (UniProt)

Protein: Catalase
Function: Catalyzes the degradation of hydrogen peroxide (H(2)O(2)) generated by peroxisomal oxidases to water and oxygen, thereby protecting cells from the toxic effects of hydrogen peroxide. Promotes growth of cells including T-cells, B-cells, myeloid leukemia cells, melanoma cells, mastocytoma cells and normal and transformed fibroblast cells.
Subcellular location: Peroxisome matrix.
Associated conditions: Acatalasemia (ACATLAS).

Why its pathway is in the library

Mitochondrial dysfunction and oxidative stress are reported in PFS/PSSD patient work; energy failure plausibly contributes to fatigue, cognitive, and sexual symptoms.

Written for the whole mitochondria & energy family, not for CAT specifically.

Mentioned in 0 corpus records

No corpus record names CAT directly yet. It is in the library because it sits in a pathway the corpus tracks (Mitochondria & energy).

Also in mitochondrial function and energy

All 33 genes

Browse by family on the gene families page.