Pathway candidateNCBI-verifiedprotein-coding

COX10

cytochrome c oxidase assembly factor heme A:farnesyltransferase COX10

NCBI Gene: 1352 Ensembl GeneCards UniProt: Q12887

Pathway candidate — not linked to PFS or PSSD by any record here

COX10 is in the library because it belongs to the mitochondria & energy family. No study, report or commentary in the corpus names it, so a variant in COX10 is not, by itself, evidence of anything related to post-drug syndromes.

Gene summary

A protein-coding gene on chromosome 17 (mitochondrial function and energy). Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes.

Source: NCBI Gene, accessed 2026-10-07.

Protein reference (UniProt)

Protein: Protoheme IX farnesyltransferase, mitochondrial
Function: Converts protoheme IX and farnesyl diphosphate to heme O (By similarity).
Subcellular location: Mitochondrion membrane.
Associated conditions: Mitochondrial complex IV deficiency, nuclear type 3 (MC4DN3).

Source: UniProtKB/Swiss-Prot Q12887, release 2026_03, licensed CC BY 4.0. This is the protein’s normal biology, not evidence about post-drug syndromes; associated conditions are inherited disorders of the gene, not PFS, PSSD or PRSD.

Why its pathway is in the library

Mitochondrial dysfunction and oxidative stress are reported in PFS/PSSD patient work; energy failure plausibly contributes to fatigue, cognitive, and sexual symptoms.

Written for the whole mitochondria & energy family, not for COX10 specifically.

Mentioned in 0 corpus records

No corpus record names COX10 directly yet. It is in the library because it sits in a pathway the corpus tracks (Mitochondria & energy).

Also in mitochondrial function and energy

All 33 genes

Browse by family on the gene families page.

Pathway candidateNCBI-verifiedprotein-coding

COX10

cytochrome c oxidase assembly factor heme A:farnesyltransferase COX10

Chromosome 17Mitochondria & energy

NCBI Gene: 1352 Ensembl GeneCards UniProt: Q12887

Pathway candidate — not linked to PFS or PSSD by any record here

Gene summary

Source: NCBI Gene, accessed 2026-10-07.

Protein reference (UniProt)

Protein: Protoheme IX farnesyltransferase, mitochondrial
Function: Converts protoheme IX and farnesyl diphosphate to heme O (By similarity).
Subcellular location: Mitochondrion membrane.
Associated conditions: Mitochondrial complex IV deficiency, nuclear type 3 (MC4DN3).

Why its pathway is in the library

Mitochondrial dysfunction and oxidative stress are reported in PFS/PSSD patient work; energy failure plausibly contributes to fatigue, cognitive, and sexual symptoms.

Written for the whole mitochondria & energy family, not for COX10 specifically.

Mentioned in 0 corpus records

No corpus record names COX10 directly yet. It is in the library because it sits in a pathway the corpus tracks (Mitochondria & energy).

Also in mitochondrial function and energy

All 33 genes

Browse by family on the gene families page.