Pathway candidateNCBI-verifiedprotein-coding

MT-CYB

cytochrome b

NCBI Gene: 4519 GeneCards UniProt: P00156

Pathway candidate — not linked to PFS or PSSD by any record here

MT-CYB is in the library because it belongs to the mitochondria & energy family. No study, report or commentary in the corpus names it, so a variant in MT-CYB is not, by itself, evidence of anything related to post-drug syndromes.

Gene summary

A protein-coding gene on chromosome MT (mitochondrial) (mitochondrial function and energy). Predicted to enable electron transfer activity; metal ion binding activity; and oxidoreductase activity. Predicted to contribute to quinol-cytochrome-c reductase activity.

Source: NCBI Gene, accessed 2026-10-07.

Protein reference (UniProt)

Protein: Cytochrome b
Function: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis (By similarity).
Subcellular location: Mitochondrion inner membrane.
Associated conditions: Cardiomyopathy, infantile histiocytoid (CMIH); Leber hereditary optic neuropathy (LHON).

Source: UniProtKB/Swiss-Prot P00156, release 2026_03, licensed CC BY 4.0. This is the protein’s normal biology, not evidence about post-drug syndromes; associated conditions are inherited disorders of the gene, not PFS, PSSD or PRSD.

Why its pathway is in the library

Mitochondrial dysfunction and oxidative stress are reported in PFS/PSSD patient work; energy failure plausibly contributes to fatigue, cognitive, and sexual symptoms.

Written for the whole mitochondria & energy family, not for MT-CYB specifically.

Mentioned in 0 corpus records

No corpus record names MT-CYB directly yet. It is in the library because it sits in a pathway the corpus tracks (Mitochondria & energy).

Also in mitochondrial function and energy

All 33 genes

Browse by family on the gene families page.

Pathway candidateNCBI-verifiedprotein-coding

MT-CYB

cytochrome b

Chromosome MTMitochondria & energy

NCBI Gene: 4519 GeneCards UniProt: P00156

Pathway candidate — not linked to PFS or PSSD by any record here

Gene summary

Source: NCBI Gene, accessed 2026-10-07.

Protein reference (UniProt)

Protein: Cytochrome b
Function: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis (By similarity).
Subcellular location: Mitochondrion inner membrane.
Associated conditions: Cardiomyopathy, infantile histiocytoid (CMIH); Leber hereditary optic neuropathy (LHON).

Why its pathway is in the library

Mitochondrial dysfunction and oxidative stress are reported in PFS/PSSD patient work; energy failure plausibly contributes to fatigue, cognitive, and sexual symptoms.

Written for the whole mitochondria & energy family, not for MT-CYB specifically.

Mentioned in 0 corpus records

No corpus record names MT-CYB directly yet. It is in the library because it sits in a pathway the corpus tracks (Mitochondria & energy).

Also in mitochondrial function and energy

All 33 genes

Browse by family on the gene families page.