Pathway candidateNCBI-verifiedprotein-coding

SOD2

superoxide dismutase 2

NCBI Gene: 6648 Ensembl GeneCards UniProt: P04179

Pathway candidate — not linked to PFS or PSSD by any record here

SOD2 is in the library because it belongs to the mitochondria & energy family. No study, report or commentary in the corpus names it, so a variant in SOD2 is not, by itself, evidence of anything related to post-drug syndromes.

Gene summary

A protein-coding gene on chromosome 6 (mitochondrial function and energy). This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit.

Source: NCBI Gene, accessed 2026-10-07.

Protein reference (UniProt)

Protein: Superoxide dismutase [Mn], mitochondrial
Function: Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
Subcellular location: Mitochondrion matrix.
Associated conditions: Microvascular complications of diabetes 6 (MVCD6).

Source: UniProtKB/Swiss-Prot P04179, release 2026_03, licensed CC BY 4.0. This is the protein’s normal biology, not evidence about post-drug syndromes; associated conditions are inherited disorders of the gene, not PFS, PSSD or PRSD.

Why its pathway is in the library

Mitochondrial dysfunction and oxidative stress are reported in PFS/PSSD patient work; energy failure plausibly contributes to fatigue, cognitive, and sexual symptoms.

Written for the whole mitochondria & energy family, not for SOD2 specifically.

Mentioned in 0 corpus records

No corpus record names SOD2 directly yet. It is in the library because it sits in a pathway the corpus tracks (Mitochondria & energy).

Also in mitochondrial function and energy

All 33 genes

Browse by family on the gene families page.

Pathway candidateNCBI-verifiedprotein-coding

SOD2

superoxide dismutase 2

Chromosome 6Mitochondria & energy

NCBI Gene: 6648 Ensembl GeneCards UniProt: P04179

Pathway candidate — not linked to PFS or PSSD by any record here

Gene summary

Source: NCBI Gene, accessed 2026-10-07.

Protein reference (UniProt)

Protein: Superoxide dismutase [Mn], mitochondrial
Function: Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
Subcellular location: Mitochondrion matrix.
Associated conditions: Microvascular complications of diabetes 6 (MVCD6).

Why its pathway is in the library

Mitochondrial dysfunction and oxidative stress are reported in PFS/PSSD patient work; energy failure plausibly contributes to fatigue, cognitive, and sexual symptoms.

Written for the whole mitochondria & energy family, not for SOD2 specifically.

Mentioned in 0 corpus records

No corpus record names SOD2 directly yet. It is in the library because it sits in a pathway the corpus tracks (Mitochondria & energy).

Also in mitochondrial function and energy

All 33 genes

Browse by family on the gene families page.