Re: I collect more and more labsgenomedutch tests…
u/drwillpowers
r/DrWillPowers2026-04-05T17:54:43Z
Dr Will Powers’ own statements and theorizing
Summary (paraphrased)
Powers lists his diagnostic array for PFS: blood testosterone, blood DHT, blood DHEAS, blood 3α-androstanediol glucuronide, a urinary DUTCH complete panel, and whole-genome sequencing reviewed against the gene list from his posts. He claims he has yet to find a PFS patient who doesn't fail this array — every one has at least one strikingly abnormal result. He reiterates the thousand-ways-to-cause-it framing: taking the drug on top of a built-in genetic anomaly produces chaos from the combined genetic plus drug-induced enzyme deficiency.
Key points (paraphrased)
- Diagnostic array: serum T, DHT, DHEAS, 3α-androstanediol glucuronide + urinary DUTCH + whole-genome sequencing of his gene list.
- Claim: zero PFS patients tested have passed the full array; all show at least one major anomaly.
- Gene–drug interaction model restated: inborn anomaly + drug = combined enzyme deficiency → chaos.
Why it’s in the corpus
Powers' canonical biomarker panel for PFS — the operational definition he uses to classify patients — essential for the corpus's diagnostics/methods section and for comparing his criteria against literature case definitions.
Context — the post Powers was replying toVerbatim third-party text, shown for context only — not Powers’ statement. Usernames removed.ShowHide
Powers' comment replies to a community member:
A lot of the science kind of went over my head here but I have a general understanding of what you're saying. I'm curious if there's any way I can test myself and send you the results for your data? I'm a one-pill case with every. single. symptom. so probably about as purely PFS as you can get. What test would one do to get this info?
(Parent context recovered from the r.genit.al mirror on 2026-10-07; Powers' comment text itself is from John's user-provided export.)
Some fields on this page come from the release’s Markdown edition, which carries text the JSON edition omits.
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Re: I collect more and more labsgenomedutch tests…
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Possible PFS Mechanism Identified — Help Us Gather Patient Data
not u/drwillpowers
The video presents Powers' Reddit post on a newly identified candidate PFS mechanism and organizes community data collection around three tests: a morning hormone panel, a blood androstanediol glucuronide test, and the DUTCH urine steroid test, with strict…
DWP-0042026PFSCore corpus
