Epigenetic side-effects of common pharmaceuticals: a potential new field in medicine and pharmacology
Csoka, Antonei B.; Szyf, Moshe
Medical Hypotheses · 73(5):770-7802009
Abstract (paraphrased)
Proposes that common pharmaceuticals can cause lasting epigenetic modifications (DNA methylation, chromatin changes) as side effects — a new field of "pharmacoepigenetics" — potentially explaining persistent post-treatment syndromes.
Plain-language summary (paraphrased)
A big-picture theory paper arguing that many drugs may leave epigenetic "scars" — lasting changes to gene regulation — that explain side effects persisting long after the drug is gone. It provides the conceptual umbrella under which PFS, PSSD and similar syndromes can all fit.
Why it’s in the corpus
Theoretical foundation for drug-induced epigenetics as a general phenomenon; underpins the shared-mechanism framing of all post-drug syndromes.
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