AVPR1A
arginine vasopressin receptor 1A
Pathway candidate — not linked to PFS or PSSD by any record here
Gene summary
A protein-coding gene on chromosome 12 (neuroendocrine and peptide signaling). The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1B, V2R and OXT receptors.
Source: NCBI Gene, accessed 2026-10-07.
Protein reference (UniProt)
- Protein
Vasopressin V1a receptor
- Function
Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl-inositol-calcium second messenger system. Has been involved in social behaviors, including affiliation and attachment.
- Subcellular location
Cell membrane.
Source: UniProtKB/Swiss-Prot P37288, release 2026_03, licensed CC BY 4.0. This is the protein’s normal biology, not evidence about post-drug syndromes; associated conditions are inherited disorders of the gene, not PFS, PSSD or PRSD.
Why its pathway is in the library
Peptide-hormone and related signaling modulates sexual function, stress, and behavior — symptom domains prominent in PSSD/PFS.
Written for the whole neuroendocrine signaling family, not for AVPR1A specifically.
Mentioned in 0 corpus records
No corpus record names AVPR1A directly yet. It is in the library because it sits in a pathway the corpus tracks (Neuroendocrine signaling).
Also in neuroendocrine and peptide signaling
All 12 genes- GNB3
G protein subunit beta 3
chr 12· Neuroendocrine signaling· 1 record - AVPR1B
arginine vasopressin receptor 1B
chr 1· Neuroendocrine signaling· Pathway candidate - AVPR2
arginine vasopressin receptor 2
chr X· Neuroendocrine signaling· Pathway candidate - MC4R
melanocortin 4 receptor
chr 18· Neuroendocrine signaling· Pathway candidate - NOS1
nitric oxide synthase 1
chr 12· Neuroendocrine signaling· Pathway candidate - NOS3
nitric oxide synthase 3
chr 7· Neuroendocrine signaling· Pathway candidate - NPY
neuropeptide Y
chr 7· Neuroendocrine signaling· Pathway candidate - NPY1R
neuropeptide Y receptor Y1
chr 4· Neuroendocrine signaling· Pathway candidate
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