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Not medical advice. A living research archive of historical and continually changing sources, for research and personal reference only. Summaries are paraphrases — verify against the originals. Full disclaimer
Not medical advice. A living research archive of historical and continually changing sources, for research and personal reference only. Summaries are paraphrases — verify against the originals. Full disclaimer
One-carbon metabolism generates S-adenosylmethionine, the methyl donor for DNA and histone methylation — the epigenetic layer implicated in persistent post-drug changes. Powers reports high MTHFR variant rates in his patient population (unpublished, adjacent work).
Sorted by how often each gene is cited in corpus records, then alphabetically.
methylenetetrahydrofolate reductase
adenosylhomocysteinase
betaine--homocysteine S-methyltransferase
5-methyltetrahydrofolate-homocysteine methyltransferase
5-methyltetrahydrofolate-homocysteine methyltransferase reductase