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Not medical advice. A living research archive of historical and continually changing sources, for research and personal reference only. Summaries are paraphrases — verify against the originals. Full disclaimer
Not medical advice. A living research archive of historical and continually changing sources, for research and personal reference only. Summaries are paraphrases — verify against the originals. Full disclaimer
These enzymes build and interconvert androgens, estrogens, progestogens, glucocorticoids, and neurosteroids from cholesterol. 5-alpha-reductase inhibitors act directly inside this network (SRD5A1/2/3), and SSRIs can alter neurosteroid tone downstream — so inherited variation here is a prime candidate for susceptibility to persistent post-drug phenotypes.
Sorted by how often each gene is cited in corpus records, then alphabetically.
steroid 5 alpha-reductase 2
steroid 5 alpha-reductase 1
aldo-keto reductase family 1 member C2
aldo-keto reductase family 1 member C3
cytochrome P450 family 17 subfamily A member 1
aldo-keto reductase family 1 member C4
aldo-keto reductase family 1 member C1
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
steroid 5 alpha-reductase 3
cytochrome P450 family 19 subfamily A member 1
cytochrome P450 family 11 subfamily A member 1
cytochrome P450 family 21 subfamily A member 2
hydroxysteroid 17-beta dehydrogenase 2
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
aldo-keto reductase family 1 member D1
steroidogenic acute regulatory protein
translocator protein
cytochrome P450 family 11 subfamily B member 1
cytochrome P450 family 11 subfamily B member 2
hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase
hydroxysteroid 11-beta dehydrogenase 1
hydroxysteroid 11-beta dehydrogenase 2
hydroxysteroid 17-beta dehydrogenase 1
hydroxysteroid 17-beta dehydrogenase 3
hydroxysteroid 17-beta dehydrogenase 4
hydroxysteroid 17-beta dehydrogenase 6
hydroxysteroid 17-beta dehydrogenase 7
hydroxysteroid 17-beta dehydrogenase 10
hydroxysteroid 17-beta dehydrogenase 12
hydroxysteroid 17-beta dehydrogenase 13
hydroxysteroid 17-beta dehydrogenase 14
retinol dehydrogenase 5
retinol dehydrogenase 16
StAR related lipid transfer domain containing 3
StAR related lipid transfer domain containing 4
StAR related lipid transfer domain containing 5
StAR related lipid transfer domain containing 6
StAR related lipid transfer domain containing 10